The covid-19  stays in the brain for months, which can cause symptoms neuropsychiatric as encephalitis, agitation, confusion, delirium and long – term depression and anxiety, according to cases reviewed in the world and published in scientific magazines, documented the General Hospital of Mexico.

Hortencia had covid-19 more than 20 days ago. She recovered, but since then she woke up with tremors in her body, she felt anxiety, her back and brain hurt.

“I’m out, but it left me very tired, depressed and very anxious. My body was very shaky, with fear, “shared the Veracruz during the presentation” Neuropsychiatric symptoms in the patient with COVID-19 “given by Homero Maldonado Mendoza, a psychiatrist attached to the Mental Health Service of the General Hospital of Mexico” Dr. Eduardo Liceaga ”. The doctor recommended that the woman go for psychiatric care to prevent these symptoms from progressing.

Neuropsychiatric complications have been reported in the psychiatric doctor Maldonado Mendoza, who mainly in Asian countries, where it was the first epicenter of the pandemic that has attacked almost 8 million people in the world. The long-term impact on the COVID-19 patient implies a risk factor for increasing mortality, and those who survive have cognitive consequences such as confusion, agitation, delirium, encephalitis and, in the long term, depression and anxiety, which will decrease quality of life.

One hypothesis explains that SARS-VOC-2 enters the Central Nervous System through the nasal epithelium, which affects the olfactory bulb; another proposes that the virus seeps into the bloodstream; and a third option would be that the body generates an inflammatory response and antibody production. In past epidemics of SARS-CoV-1 and MERS-CoV, viruses similar to that caused by COVID-19, the virus has been seen to persist in the Central Nervous System after treatment. It stays in parts of the brain for a time.

The Lancet Psichiatry magazine  reported symptoms such as confusion, agitation and insomnia in COVID patients from Japan, France, China and Hong Kong. In Wuhan, China, 217 hospitalized patients with cerebrovascular complications, encephalopathies, and neuromuscular disorders were registered. In France, 49 patients were affected with confusion and abnormalities on MRI.

Chronic disorders such as depression or anxiety may appear in the coming months, especially in patients hospitalized in intensive care, but the current data is limited. “Normally they are seen in phases after the pandemic,” said Maldonado Mendoza. In survivors of SARS-CoV-1, another type of coronavirus, after infection they had symptoms of post-traumatic stress disorder, depression, panic, and obsessive-compulsive disorder.

Another major complication seen in patients with COVID-19 worldwide is cerebrovascular disease, said the psychiatrist based on articles in the scientific journals Jama Neurology and New England Journal of Medicine.

“Cerebrovascular disease has been seen in patients with COVID-19 that mainly affects elderly patients, who have already had some significant cardiovascular risk, who had a severe coronavirus infection and caused respiratory distress,” observed the doctor. .

Regarding encephalitis, the psychiatrist attached to the Mental Health Service of the General Hospital of Mexico said that it can be due to the inflammatory response caused by SARS-VOC-2 in the brain generated through antibodies against the virus.

“The encephalitis pictures come to present themselves in various ways, from seizures, fevers, headaches to behavioral disturbances and psychosis,” he said. Although the published cases are still few. In Wuhan, a 56-year-old woman came to the emergency department with changes in the level of consciousness due to encephalitis; a 24-year-old man arrived with generalized epileptic seizures and changes in the state of consciousness; and a 23-year-old man had psychotic symptoms, agitation, and a history of substance use, according to the Journal of Neurology.

Regarding patients who already had mental illnesses before becoming infected with coronavirus, the biological and psychological effect is still uncertain. In a series of 114 patients, altered mental status was reported in 39 of them, but only two had the previous mental condition.